Ulcerative colitis


Patient Presentation:
A twenty-one year old female presents to her primary care physician with complaints of frequent diarrhea and cramping. Her last several bouts have included small amounts of blood, and she grew concerned enough to make an appointment. She is 5’5’’, weighs 120 pounds, and is also complaining of low energy. Her blood pressure is 105/70, heart rate 85, temperature 37.9, respiratory rate 18. She states she has had no recent travel and has not been taking any medications.

Differential List:
Crohn’s disease, ulcerative colitis, bacterial or viral infection

Diagnosis:
A CBC was drawn to evaluate for anemia due to the patient’s complaints of lethargy and bloody stools. Her HGB was a low normal (13). Stool cultures were taken to evaluate for an infection vs inflammatory process. White blood cells were discovered in the stool culture, and a colonoscopy was scheduled. The colonoscopy revealed continuous inflammation and reddened mucosa of the recto-sigmoid colon, and biopsies were taken. Biopsies revealed inflammation of the crypts and distortion of the crypt architecture. A diagnosis of ulcerative colitis was made.

Treatment:
The patient was started on mesalazine to suppress the inflammatory response and alleviate her cramping pain. The patient began a food diary, noting foods that seemed to increase her symptoms.

Outcome:
The patient’s ulcerative colitis went into remission during her course of mesalazine, and she remains on a maintenance dose. Her food journal revealed a problem with dairy and caffeinated beverages, and she has cut them out of her diet, supplementing with a vitamin D and calcium vitamin daily.